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Tyrosine: Function, Foods and Effect Under Stress

Tyrosine is the starting material for dopamine, noradrenaline and thyroid hormones. Read here what the amino acid really does.

Tyrosine: Function, Foods and Effect Under Stress

Tyrosine, more precisely L-tyrosine, is a non-essential amino acid that the body can make itself from the essential amino acid phenylalanine. Even so, tyrosine is important for the body, because it serves as the starting material for several messenger substances and hormones, including dopamine, noradrenaline and the thyroid hormones.

In this guide you will learn what functions tyrosine performs in the body, which foods contain it, what research says about its effect on concentration and performance under stress, and how to judge a dose as a reference.

01

What is tyrosine and what is it needed for

Tyrosine is one of the semi-essential amino acids: the body can form it itself, but only from sufficient available phenylalanine. If phenylalanine is lacking in the diet, the body's own tyrosine production automatically falls as well. Tyrosine is formed mainly in the liver.

As a protein building block, tyrosine is part of many of the body's own proteins. Its particular importance lies, however, in the fact that it is the precursor of the catecholamines dopamine, noradrenaline and adrenaline, as well as of the thyroid hormones thyroxine and triiodothyronine. In addition, tyrosine is involved in the formation of melanin, the pigment that gives skin and hair their colour.

These messenger substances are released particularly under physical and mental strain. Adrenaline and noradrenaline are among the classic stress hormones, which are released in situations of increased demand, such as during sport, exams or sudden time pressure, and make the body briefly more ready to perform. Dopamine, in turn, is often linked with motivation, drive and a feeling of reward.

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02

Tyrosine-rich foods

Daily tyrosine needs are generally covered well by a balanced, protein-rich diet, since tyrosine occurs in practically all protein-containing foods.

FoodTypical tyrosine content per 100 g (reference value)
Hard cheeseabout 1 to 1.8 g
Soybeansabout 1.5 g
Peanutsabout 1.1 g
Fishabout 0.7 to 0.9 g
Chicken breastabout 0.8 g
Eggsabout 0.5 g

These values vary by product and should be understood as a rough guide, not exact laboratory values. Anyone who eats a balanced, high-protein diet generally does not need to worry about an insufficient supply of tyrosine. Targeted supplementation with isolated tyrosine is therefore mainly a topic in special situations of strain, and not in normal everyday life with a balanced diet.

03

Tyrosine under stress and mental strain

One particular focus of research is the role of tyrosine under acute stress. The basic idea: under strong, sustained stress, for example from lack of sleep, cold, noise or high cognitive demands, the consumption of noradrenaline and dopamine in the brain can rise and the available stores can shrink. Additional tyrosine is meant to help secure the supply of these messenger substances in such situations.

In sport, tyrosine is occasionally used mainly for endurance efforts or under special stress conditions such as heat or altitude, on the assumption that it can counteract central fatigue. Under normal, moderate training conditions without an additional stress factor, a noticeable effect is by contrast considerably less likely.

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04

What the research says

The evidence on tyrosine is inconsistent and depends heavily on the particular stress situation. Under acute, repeated stress, for example in studies on sleep deprivation, cold exposure or military training, some studies show an improvement in certain cognitive performance such as attention and working memory with tyrosine. Under everyday, less extreme conditions, the effects are considerably smaller or cannot be demonstrated.

A further aspect concerns individual differences: some studies suggest that tyrosine shows a measurable effect mainly in people with an already low dopamine level or under particularly heavy strain, whereas in those in good baseline condition hardly any difference can be found. This at least partly explains why study results on tyrosine are so inconsistent overall.

For purely athletic performance, such as strength, sprinting or classic endurance performance under normal training conditions, the evidence is thin overall and the existing studies do not give a uniform picture. It would therefore not be correct to describe tyrosine across the board as a performance booster for everyday training. A more realistic classification is as a possible building block to support mental performance under particular stress, while the effect on classic athletic performance parameters is far less well documented. Dietary supplements are also no substitute for a balanced diet and enough sleep, which likewise play a central role in the body's own stress processing.

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05

Dose and intake as a guide

In studies on acute stress, amounts in the range of about 100 to 150 mg per kilogram of body weight were often used, spread across the day or as a single dose before the stressful situation. Commercially available products usually contain considerably smaller amounts per capsule or portion, which is why you should go by the packaging information of the respective product instead of calculating study amounts yourself without checking.

Tyrosine is usually offered in capsule or powder form and taken with plenty of water. Taking it on an empty stomach is often recommended, since tyrosine then competes with fewer other amino acids for absorption in the gut.

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06

Tyrosine and sport: practical perspective

In strength sports, tyrosine plays a considerably smaller role than, for example, creatine or classic pre-workout formulations with caffeine. When tyrosine is used in a training context, it is mostly for particularly long or demanding endurance efforts, for competitions in adverse conditions such as great heat or cold, or in phases with additional everyday stress and little sleep. In these situations the theoretical approach of supporting the supply of stress hormones in the brain is easiest to follow.

For normal strength training without particular stress, by contrast, there is no convincing basis for the claim that tyrosine noticeably improves performance. Anyone who wants to improve their training performance generally benefits far more from sufficient carbohydrate intake, enough sleep and a well-thought-out training plan than from an isolated amino acid such as tyrosine.

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07

Side effects and important notes

At the usual amounts, tyrosine is considered well tolerated by healthy adults. In rare cases, headaches, nausea or stomach complaints can occur. Particular caution is advised with thyroid conditions, since tyrosine is involved in the formation of thyroid hormones. Tyrosine should also not be taken without medical advice alongside antidepressants from the group of MAO inhibitors, as interactions can occur.

If you have existing conditions, are pregnant or breastfeeding, or take medication, you should always discuss taking tyrosine with a doctor beforehand. Dietary supplements are no substitute for a balanced diet, which through sufficient protein intake already provides a good baseline of tyrosine.

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08

Frequently asked questions

Does tyrosine make you more alert and able to perform?

Under particular stress, such as lack of sleep, it can support certain cognitive functions. Tyrosine is not, however, a general stimulant or a replacement for enough sleep.

Is tyrosine important for muscle building?

As a protein building block, tyrosine contributes to the general amino acid pool, but for muscle building in the narrower sense it plays a minor role compared with essential amino acids such as leucine.

Can I develop a tyrosine deficiency?

With a balanced, high-protein diet, a deficiency is rare. The risk is higher with a very one-sided diet or certain metabolic disorders, which should be checked by a doctor.

When should I take tyrosine?

Taking it about 30 to 60 minutes before the stressful situation is often recommended, for example before an exam or a night shift. Follow the packaging information of the respective product.

Does tyrosine work like caffeine?

No. Caffeine has a direct stimulating effect via the central nervous system, whereas tyrosine merely supplies a building block for messenger substances whose formation depends on further factors anyway. An immediate, caffeine-like stimulant effect is not to be expected from tyrosine, even though both substances are occasionally advertised in the same product category.

Can I take tyrosine long term?

At the usual amounts there are no known indications of problems with longer use in healthy adults. If you plan to take it long term, especially with existing conditions, consulting a doctor still makes sense.

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